INDICATION: NEXPLANON is a prescription medication for the prevention of pregnancy in women.
IMPORTANT SAFETY INFORMATION: You should not use NEXPLANON if you are pregnant or think you may be pregnant; have or have had blood clots; have liver disease or a liver tumor; have unexplained vaginal bleeding; have breast cancer or any other cancer that is sensitive to progestin (a female hormone), now or in the past; or are allergic to anything in NEXPLANON. Talk to a trained healthcare professional about using NEXPLANON if you have diabetes, high cholesterol or triglycerides, headaches, gallbladder or kidney problems, history of depressed mood, high blood pressure, allergy to numbing medicines (anesthetics) or medicines used to clean your skin (antiseptics). These medicines will be used when the implant is placed into or removed from your arm.

Indication

NEXPLANON is a prescription birth control for the prevention of pregnancy in women.

Important Safety Information

You should not use NEXPLANON if you are pregnant or think you may be pregnant; have or have had blood clots; have liver disease or a liver tumor; have unexplained vaginal bleeding; have breast cancer or any other cancer that is sensitive to progestin (a female hormone), now or in the past; or are allergic to anything in NEXPLANON. Talk to a trained healthcare professional about using NEXPLANON if you have diabetes, high cholesterol or triglycerides, headaches, gallbladder or kidney problems, history of depressed mood, high blood pressure, allergy to numbing medicines (anesthetics) or medicines used to clean your skin (antiseptics). These medicines will be used when the implant is placed into or removed from your arm.

REPLACING YOUR IMPLANT

it’s year 3 and you’d like to continue using NEXPLANON

While you need to have your NEXPLANON implant removed by the end of the third year, you can also get a new implant inserted in the same removal procedure.

You should have your card at home or with your medical records with the date that the NEXPLANON implant was inserted along with the date that it needs to be removed.

Because your NEXPLANON implant must be removed by the end of the third year, it’s important for you to stay on top of your removal date.

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actor portrayal

set up an appointment with a trained healthcare professional to remove NEXPLANON

A trained healthcare professional can remove NEXPLANON at any time during the 3-year period. If you want to keep it for 3 years, remember to remove it by the date shown on your user card for NEXPLANON.

Removal of the NEXPLANON implant involves a minor surgical procedure by a trained healthcare professional and can be performed in the office through a small incision in your arm where NEXPLANON is located.

Learn about removal
Visual of Inner Arm Showcasing Position of Implant Insertion

during the same visit, a new NEXPLANON can be reinserted into the same location

Since the area has already been sterilized and numbing medication has been administered, a trained healthcare professional can insert a new NEXPLANON into the same area of your inner upper arm.

Once inserted, both patient and the trained healthcare professional will then feel the area to ensure the implant is placed correctly. If it is, the healthcare professional will cover the site where NEXPLANON was placed with 2 bandages. Leave the top bandage on for 24 hours. Keep the smaller bandage clean, dry, and in place for 3 to 5 days.

Learn more about insertion

following insertion, a trained healthcare professional will cover the insertion site with 2 bandages

Leave the top bandage on for 24 hours. Keep the smaller bandage clean, dry, and in place for 3 to 5 days.

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don’t use NEXPLANON if you …

  • Are pregnant or think you may be pregnant

  • Have, or have had blood clots, such as blood clots in your leg (deep vein thrombosis), lungs (pulmonary embolism), eyes (total or partial blindness), heart (heart attack), or brain (stroke)

  • Have liver disease or a liver tumor

  • Have unexplained vaginal bleeding

  • Have breast cancer or any other cancer that is sensitive to progestin (a female hormone), now or in the past

  • Are allergic to anything in NEXPLANON

  • Are pregnant or think you may be pregnant

  • Have, or have had blood clots, such as blood clots in your leg (deep vein thrombosis), lungs (pulmonary embolism), eyes (total or partial blindness), heart (heart attack), or brain (stroke)

  • Have liver disease or a liver tumor

  • Have unexplained vaginal bleeding

  • Have breast cancer or any other cancer that is sensitive to progestin (a female hormone), now or in the past

  • Are allergic to anything in NEXPLANON

tell your doctor if you have or have had any of these conditions

Your healthcare professional can suggest a different method of birth control.

DIABETES

HIGH CHOLESTEROL

HIGH TRIGLYCERIDES

HAVE HEADACHES

GALLBLADDER PROBLEMS

KIDNEY PROBLEMS

HISTORY OF DEPRESSION

HIGH BLOOD PRESSURE

Before getting NEXPLANON, please tell the trained healthcare professional if you have any allergies to numbing medicines or antiseptics used to clean your skin. These medicines will be used when the implant is placed into or removed from your arm.

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Indication
NEXPLANON is a prescription birth control for the prevention of pregnancy in women.

Important Safety Information

You should not use NEXPLANON if you are pregnant or think you may be pregnant; have or have had blood clots; have liver disease or a liver tumor; have unexplained vaginal bleeding; have breast cancer or any other cancer that is sensitive to progestin (a female hormone), now or in the past; or are allergic to anything in NEXPLANON.

Talk to your healthcare professional about using NEXPLANON if you have diabetes, high cholesterol or triglycerides, headaches, gallbladder or kidney problems, history of depressed mood, high blood pressure, allergy to numbing medicines (anesthetics) or medicines used to clean your skin (antiseptics). These medicines will be used when the implant is placed into or removed from your arm.

Immediately after the NEXPLANON implant has been placed, you and your healthcare professional should check that the implant is in your arm by feeling for it. If at any time you cannot feel the NEXPLANON implant, contact your healthcare professional immediately and use a non-hormonal birth control method (such as condoms) until your healthcare professional confirms that the implant is in place. You may need special tests to check that the implant is in place or to help find the implant when it is time to take it out.

The implant may not be actually in your arm due to failed insertion. If this happens, you may become pregnant. Removal of the implant may be very difficult or impossible if the implant is not where it should be. Special procedures, including surgery in the hospital, may be needed to remove the implant. If the implant is not removed, then the effects of NEXPLANON will continue for a longer period of time. Other problems related to insertion and removal may also occur, including vasovagal reactions (such as a drop in blood pressure, dizziness, or fainting), pain, irritation, swelling, bruising, numbness and tingling, scarring, infection, injury to the nerves or blood vessels, and breaking of the implant. Additionally, the implant may come out by itself. You may become pregnant if the implant comes out by itself. Use a back-up birth control method and call your healthcare professional right away if the implant comes out.

The most common side effect of NEXPLANON is a change in your normal menstrual bleeding pattern. In studies, one out of ten women stopped using the implant because of an unfavorable change in their bleeding pattern. You may experience longer or shorter bleeding during your periods or have no bleeding at all. The time between periods may vary, and you may also have spotting in between periods.

If you become pregnant while using NEXPLANON, you have a slightly higher chance that the pregnancy will be ectopic (occurring outside the womb) than do women who do not use birth control. Ectopic pregnancies can cause serious internal bleeding, infertility, and even death. Call your healthcare professional right away if you think you are pregnant or have unexplained lower stomach (abdominal) pain.

The use of NEXPLANON may also increase your chance of serious blood clots, especially if you have other risk factors, such as smoking. If you smoke and want to use NEXPLANON, you should quit. Serious blood clots can occur within blood vessels of different parts of the body, including legs (deep vein thrombosis), lungs (pulmonary embolism), brain (stroke), heart (heart attack), and eyes (total or partial blindness). It is possible to die from a problem caused by a blood clot, such as a heart attack or stroke. Tell your healthcare professional at least 4 weeks before if you are going to have surgery or will need to be on bed rest, because you have an increased chance of getting blood clots during surgery or bed rest.

Cysts may develop on the ovaries and usually go away without treatment, but sometimes surgery is needed to remove them.

Besides changes in menstrual bleeding patterns, other common side effects reported in women using NEXPLANON include: headaches; vaginitis (inflammation of the vagina); weight gain; acne; breast pain; viral infection such as sore throats or flu-like symptoms; stomach pain; painful periods; mood swings, nervousness, or depressed mood; back pain; nausea; dizziness; pain and pain at the site of insertion. Implants have been reported to be found in a blood vessel, including a blood vessel in the lung.

Call your healthcare professional right away if you have pain in your lower leg that does not go away; severe chest pain or heaviness in the chest; sudden shortness of breath, sharp chest pain, or coughing blood; symptoms of a severe allergic reaction, such as swollen face, tongue or throat, trouble breathing or swallowing; sudden severe headaches unlike your usual headaches; weakness or numbness in your arm, leg, or trouble speaking; sudden partial or complete blindness; yellowing of your skin or whites of your eyes, especially with fever, tiredness, loss of appetite, dark-colored urine, or light-colored bowel movements; severe pain, swelling, or tenderness in the lower stomach (abdomen); lump in your breast; problems sleeping, lack of energy, tiredness, or you feel very sad; heavy menstrual bleeding; or if you feel that the implant may have broken or bent while in your arm.

NEXPLANON does not protect against HIV or other STDs.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

Please read the accompanying Patient Information for NEXPLANON and discuss it with your healthcare professional. The physician Prescribing Information also is available.