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INDICATION: NEXPLANON is a prescription medication for the prevention of pregnancy in women.
IMPORTANT SAFETY INFORMATION: You should not use NEXPLANON if you are pregnant or think you may be pregnant; have or have had blood clots; have liver disease or a liver tumor; have unexplained vaginal bleeding; have breast cancer or any other cancer that is sensitive to progestin (a female hormone), now or in the past; or are allergic to anything in NEXPLANON. Talk to a trained healthcare professional about using NEXPLANON if you have diabetes, high cholesterol or triglycerides, headaches, gallbladder or kidney problems, history of depressed mood, high blood pressure, allergy to numbing medicines (anesthetics) or medicines used to clean your skin (antiseptics). These medicines will be used when the implant is placed into or removed from your arm.

Indication

NEXPLANON is a prescription birth control for the prevention of pregnancy in women.

Important Safety Information

You should not use NEXPLANON if you are pregnant or think you may be pregnant; have or have had blood clots; have liver disease or a liver tumor; have unexplained vaginal bleeding; have breast cancer or any other cancer that is sensitive to progestin (a female hormone), now or in the past; or are allergic to anything in NEXPLANON. Talk to a trained healthcare professional about using NEXPLANON if you have diabetes, high cholesterol or triglycerides, headaches, gallbladder or kidney problems, history of depressed mood, high blood pressure, allergy to numbing medicines (anesthetics) or medicines used to clean your skin (antiseptics). These medicines will be used when the implant is placed into or removed from your arm.

NEXPLANON: FAQS

following are the most commonly asked questions about NEXPLANON

And, of course, answers to those questions.

exploring NEXPLANON

Yes, NEXPLANON is a small (about the size of a matchstick), thin, and flexible birth control implant that provides 3 years* of continuous pregnancy prevention. It’s placed discreetly just under the skin on the inner side of your non-dominant upper arm by a trained healthcare professional.

*NEXPLANON must be removed by the end of the third year.

No, it's not an intrauterine device (IUD). It is an implant that is placed in your arm. Like an IUD, it's a long-acting birth control option. NEXPLANON lasts for 3 years.*

*NEXPLANON must be removed by the end of the third year.

NEXPLANON is 1.6 inches (4 centimeters) in length, about the size of a matchstick.

NEXPLANON is a hormone-releasing birth control implant for use by women to prevent pregnancy for up to 3 years.*

NEXPLANON prevents pregnancy in several ways. The most important way is by stopping the release of an egg from your ovary. NEXPLANON also thickens the mucus in your cervix and this change may keep sperm from reaching the egg.

NEXPLANON also changes the lining of your uterus.

*NEXPLANON must be removed by the end of the third year.

No. NEXPLANON does not contain estrogen.

NEXPLANON is over 99% effective (less than 1 pregnancy per 100 women who used NEXPLANON for 1 year) at preventing pregnancy. NEXPLANON is one of the most effective forms of birth control available.

The NEXPLANON implant must be removed by the end of the third year. A trained healthcare professional can insert a new implant under your skin after removing the old one if you choose to continue using NEXPLANON for birth control.

A trained healthcare professional can remove the implant at any time within the 3-year period. You may become pregnant as early as the first week after removal of the implant. If you do not want to get pregnant after removal of the NEXPLANON implant, you should start another birth control method, such as condoms, immediately.

The most common side effect of NEXPLANON is a change in your normal menstrual bleeding pattern. In studies, 1 in 10 women stopped using the implant because of an unfavorable change in their bleeding pattern. Your period may be longer or shorter, or you may have no bleeding at all. The time between periods may vary, and you may also have spotting in between periods.

Your healthcare professional/doctor will help you determine when to have NEXPLANON inserted. The timing will depend on whether you are currently using birth control and which method you are using. You should not use NEXPLANON if you are pregnant or think you may be pregnant.

NEXPLANON can be removed at any time by a trained healthcare professional in a minor surgical procedure during the 3-year period, but must be removed by the end of the third year. For more information about how to get NEXPLANON removed, click here.

using NEXPLANON

Call your healthcare professional right away if you have:

  • Pain in your lower leg that does not go away
  • Severe chest pain or heaviness in your chest
  • Sudden shortness of breath, sharp chest pain, or coughing blood
  • Symptoms of a severe allergic reaction, such as swollen face, tongue or throat, trouble breathing or swallowing
  • Sudden severe headache unlike your usual headaches
  • Weakness or numbness in your arm, leg, or trouble speaking
  • Sudden partial or complete blindness
  • Yellowing of your skin or whites of your eyes, especially with fever, tiredness, loss of appetite, dark-colored urine, or light-colored bowel movements
  • Severe pain, swelling, or tenderness in the lower stomach (abdomen)
  • Lump in your breast
  • Problems sleeping, lack of energy, tiredness, or you feel very sad
  • Heavy menstrual bleeding
  • Feeling that the implant may have broken or bent while in your arm

Tell your healthcare professional about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. Certain medicines may make NEXPLANON less effective, including:

  • Aprepitant
  • Barbiturates
  • Bosentan
  • Carbamazepine
  • Felbamate
  • Griseofulvin
  • Oxcarbazepine
  • Phenytoin
  • Rifampin
  • St. John’s wort
  • Topiramate
  • HIV medicines
  • Hepatitis C virus medicines

Ask your healthcare professional if you’re not sure if your medicine is listed above.

If you are taking medicines or herbal products that might make NEXPLANON less effective, you and your doctor may decide to leave NEXPLANON in place; in that case, an additional, non-hormonal contraceptive should be used. Because the effect of another medicine on NEXPLANON may last up to 28 days after stopping the medicine, it is necessary to use the additional, non-hormonal contraceptive for that long.

When you’re using NEXPLANON, tell all healthcare professionals that you have NEXPLANON in place in your arm.

Do not use NEXPLANON if you:

  • Are pregnant or think you may be pregnant
  • Have, or have had blood clots, such as blood clots in your legs (deep vein thrombosis), lungs (pulmonary embolism), eyes (total or partial blindness), heart (heart attack), or brain (stroke)
  • Have liver disease or a liver tumor
  • Have unexplained vaginal bleeding
  • Have breast cancer or any other cancer that is sensitive to progestin (a female hormone), now or in the past
  • Are allergic to anything in NEXPLANON

Tell your healthcare professional if you have or have had any of the conditions listed above. Your healthcare professional can suggest a different method of birth control.

In addition, talk to your healthcare professional about using NEXPLANON if you have:

  • Diabetes
  • High cholesterol or triglycerides
  • Headaches
  • Gallbladder or kidney problems
  • A history of depressed mood
  • High blood pressure
  • An allergy to numbing medicines (anesthetics) or medicines used to clean your skin (antiseptics). These medicines will be used when the implant is placed into or removed from your arm.

You should see a healthcare professional right away if you think that you might be pregnant. It’s important to remove NEXPLANON and make sure that the pregnancy is not ectopic (occurring outside the womb). Based on experience with other hormonal contraceptives, NEXPLANON is not likely to cause birth defects.

If you’re breastfeeding your child, you may use NEXPLANON if 4 weeks have passed since you had your baby. A small amount of the hormone contained in NEXPLANON passes into your breast milk. The health of breastfed children whose mothers were using the implant has been studied up to 3 years of age in a small number of children. No effects on the growth and development of the children were seen. If you’re breastfeeding and want to use NEXPLANON, talk with a healthcare professional for more information.

You may be able to get NEXPLANON for free under the Affordable Care Act. Check with your insurance plan for cost and insurance information. You may need to pay a co-pay, deductible, or other charges.

Indication
NEXPLANON is a prescription birth control for the prevention of pregnancy in women.

Important Safety Information

You should not use NEXPLANON if you are pregnant or think you may be pregnant; have or have had blood clots; have liver disease or a liver tumor; have unexplained vaginal bleeding; have breast cancer or any other cancer that is sensitive to progestin (a female hormone), now or in the past; or are allergic to anything in NEXPLANON.

Talk to your healthcare professional about using NEXPLANON if you have diabetes, high cholesterol or triglycerides, headaches, gallbladder or kidney problems, history of depressed mood, high blood pressure, allergy to numbing medicines (anesthetics) or medicines used to clean your skin (antiseptics). These medicines will be used when the implant is placed into or removed from your arm.

Immediately after the NEXPLANON implant has been placed, you and your healthcare professional should check that the implant is in your arm by feeling for it. If at any time you cannot feel the NEXPLANON implant, contact your healthcare professional immediately and use a non-hormonal birth control method (such as condoms) until your healthcare professional confirms that the implant is in place. You may need special tests to check that the implant is in place or to help find the implant when it is time to take it out.

The implant may not be actually in your arm due to failed insertion. If this happens, you may become pregnant. Removal of the implant may be very difficult or impossible if the implant is not where it should be. Special procedures, including surgery in the hospital, may be needed to remove the implant. If the implant is not removed, then the effects of NEXPLANON will continue for a longer period of time. Other problems related to insertion and removal may also occur, including vasovagal reactions (such as a drop in blood pressure, dizziness, or fainting), pain, irritation, swelling, bruising, numbness and tingling, scarring, infection, injury to the nerves or blood vessels, and breaking of the implant. Additionally, the implant may come out by itself. You may become pregnant if the implant comes out by itself. Use a back-up birth control method and call your healthcare professional right away if the implant comes out.

The most common side effect of NEXPLANON is a change in your normal menstrual bleeding pattern. In studies, one out of ten women stopped using the implant because of an unfavorable change in their bleeding pattern. You may experience longer or shorter bleeding during your periods or have no bleeding at all. The time between periods may vary, and you may also have spotting in between periods.

If you become pregnant while using NEXPLANON, you have a slightly higher chance that the pregnancy will be ectopic (occurring outside the womb) than do women who do not use birth control. Ectopic pregnancies can cause serious internal bleeding, infertility, and even death. Call your healthcare professional right away if you think you are pregnant or have unexplained lower stomach (abdominal) pain.

The use of NEXPLANON may also increase your chance of serious blood clots, especially if you have other risk factors, such as smoking. If you smoke and want to use NEXPLANON, you should quit. Serious blood clots can occur within blood vessels of different parts of the body, including legs (deep vein thrombosis), lungs (pulmonary embolism), brain (stroke), heart (heart attack), and eyes (total or partial blindness). It is possible to die from a problem caused by a blood clot, such as a heart attack or stroke. Tell your healthcare professional at least 4 weeks before if you are going to have surgery or will need to be on bed rest, because you have an increased chance of getting blood clots during surgery or bed rest.

Cysts may develop on the ovaries and usually go away without treatment, but sometimes surgery is needed to remove them.

Besides changes in menstrual bleeding patterns, other common side effects reported in women using NEXPLANON include: headaches; vaginitis (inflammation of the vagina); weight gain; acne; breast pain; viral infection such as sore throats or flu-like symptoms; stomach pain; painful periods; mood swings, nervousness, or depressed mood; back pain; nausea; dizziness; pain and pain at the site of insertion. Implants have been reported to be found in a blood vessel, including a blood vessel in the lung.

Call your healthcare professional right away if you have pain in your lower leg that does not go away; severe chest pain or heaviness in the chest; sudden shortness of breath, sharp chest pain, or coughing blood; symptoms of a severe allergic reaction, such as swollen face, tongue or throat, trouble breathing or swallowing; sudden severe headaches unlike your usual headaches; weakness or numbness in your arm, leg, or trouble speaking; sudden partial or complete blindness; yellowing of your skin or whites of your eyes, especially with fever, tiredness, loss of appetite, dark-colored urine, or light-colored bowel movements; severe pain, swelling, or tenderness in the lower stomach (abdomen); lump in your breast; problems sleeping, lack of energy, tiredness, or you feel very sad; heavy menstrual bleeding; or if you feel that the implant may have broken or bent while in your arm.

NEXPLANON does not protect against HIV or other STDs.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

Please read the accompanying Patient Information for NEXPLANON and discuss it with your healthcare professional. The physician Prescribing Information also is available.